Those coming from a connection between species that like each other are most often accepted by both side as one of their own. The species concept for these kind of Half-Bloods is always:
Tapping into Both Cultures
(de: In beiden Kulturen daheim)
Those coming from a connection between species that only accept each other are seen with distrust. Usually they will be treated like their are of the 'other' species - not the own. The species concept for these kind of Half-Bloods is always:
Two Halves, but Nothing Fully
(de: Zwischen den Stühlen)
Half-Bloods from species that dislike each other are so unusal that it must be explicitly accepted by the GM and the rest of the group. As they bring a whole lot of potential for trouble and conflict into the group. The species concept needs to be custom-created reflecting their heritage.